Natural cholesterol breakthrough for healthy HDL, LDL, and triglyceride levels

Advanced Cholesterol Solutions (30 capsules, 30-day supply) | cholesterol supplements

Item# CHS
1 Bottle
Buy 3, Get 1 FREE
Was: $159.96
Now: $119.97
Buy 5, Get 2 FREE
Was: $279.93
Now: $199.95

Improve your cholesterol ratios—the cardio measures that really matter.

Conventional wisdom says you need to manage your total cholesterol for optimal cardiovascular health—but this is dangerously misleading. It’s far more important to focus on the individual lipid levels that make up your total cholesterol number and to balance the ratios of these lipids—what you want is high HDL, low non-oxidized LDL, and normal triglycerides.

That’s why I’m thrilled to introduce my Advanced Cholesterol Solutions, a unique, all-natural solution that works on the important sub-measures of cholesterol. This powerful formula features a breakthrough ingredient called Bergamonte® that promotes healthy cholesterol ratios by increasing HDL cholesterol while promoting normal LDL and triglycerides.

In addition to its multi-faceted ability to improve your cholesterol sub-measures, Bergamonte also supports blood vessel health and even normal blood sugar levels.

Double-blind, placebo-controlled study results

Clinical Study Results on Bergamonte

Bergamonte polyphenolic fraction (BPF) was compared to a placebo in a study of 237 men and women. In the double-blind study, researchers divided subjects into 3 different groups. Each group was divided into 3 subgroups and received either 500 mg/day BPF (69 subjects), 1,000 mg/day BPF (70 subjects), or placebo (66 subjects) for 30 days.

At the end of the trial, researchers found that BPF significantly reduced total cholesterol, LDL cholesterol and triglycerides, increased HDL cholesterol, and reduced blood glucose levels (all results statistically significant compared to placebo). In addition, there were no significant side effects or toxicity found when taking BPF, including in a group of subjects that had shown previous intolerance symptoms when using other more popular methods to better manage cholesterol.

Plus potent antioxidants to protect against cholesterol oxidation

Bergamot orange

Bergamonte: The powerful citrus extract with unique, cholesterol-balancing benefits

Bergamonte is an extract from the juice of the Bergamot orange (Citrus bergamia Risso), a small, fragrant fruit grown predominantly along the southern coast of Calabria, Italy. The extract, which is standardized for polyphenols, flavonones, and flavones, works in a number of different ways to promote healthy cholesterol levels.

One way is by inhibiting the enzyme HMG-CoA, which then causes the liver to produce less cholesterol and instead extract LDL cholesterol from the bloodstream to meet its requirements. It also reduces blood cholesterol levels by enhancing fecal sterol excretion, binding bile acids, and increasing the recycling of cholesterol in the gastrointestinal tract.

In addition to Bergamonte, I included a powerful vitamin E complex with both tocotrienols and tocopherols, and 50 mg of vitamin C in my Advanced Cholesterol Solutions formula to help reduce cholesterol oxidation—another critical factor in any effective cholesterol control effort. These important antioxidant vitamins also support healthy blood vessels.

Together, the ingredients in Advanced Cholesterol Solutions give you a revolutionary new way to support healthy cholesterol levels…naturally.

Frequently Asked Questions about Advanced Cholesterol Solutions

Are there any known Supplement/Drug Interactions?

Do not take if you are taking a statin drug. If you are pregnant or lactating, consult a healthcare provider before taking this product. If in doubt, consult with your physician before taking this or any drug or natural supplement. This supplement is not intended for children.

Are there any side effects?

There are no known major side effects of Advanced Cholesterol Solutions.

Are there any allergens in the product?

This product does not contain any of the major allergens, including soy, wheat, milk, egg, peanuts, nuts, fish, or shellfish.

Should I take CoQ10 when taking this product?

I advise anyone with cardiovascular concerns to take CoQ10 daily, and when taking any product that affects the HMG-CoA reductase enzyme, including citrus bergamot extract. I recommend taking 50–200 mg of highly bioavailable CoQ10 daily depending on your cardiovascular health needs.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Ingredients and Dosage

Doctor’s Suggested Use: Take 1 capsule daily, preferably before a meal. For extra support to maintain healthy cholesterol ratios, take 2 capsules once daily.

Serving Size: 1 capsule
Servings Per Container:

Ingredient Amount Per Serving % DV
Vitamin C (as ascorbic acid) 50 mg 83%
Bergamonte®‡Citrus Bergamia
Risso Polyphenolic Extract (from peel, 30% flavanone comprised of Neoeriocitrin, Naringin, and Neohesperidin, 1% melitidine, 2% Bruteridine)
500 mg *
Tocotrienol and Tocopherol Complex (from palm fruit) 10 mg *
*Daily Value (DV) not established.

Other ingredients: Gelatin, magnesium stearate

Note: Pregnant or lactating women should consult a health care professional before taking this product.
Keep out of reach of children.

‡Bergamonte® is a registered trademark of HP Ingredients.


Displaying 1-10 of 20


Reviewed on
4.0 out of 5 stars



Reviewed on
5.0 out of 5 stars

Cholesterol Solutions has done it for me. […] I now take one capsule of Advance Cholesterol Solutions and my HDL [and total cholesterol have improved]. I feel that they are still getting better and I will continue with that routine.


Reviewed on
4.0 out of 5 stars

I started taking this about a month ago. I haven't noticed any side effects from it. I won't have my blood levels checked for another 5 months. Then I'll be able to tell if they have made a difference along with my veggie diet and more exercise. So far, so good


Reviewed on
1.0 out of 5 stars

I took cholesterol solutions for 4 months then had a cholesterol test done. Unfortunately, I did not get the results I was looking for. My numbers were even higher than before I took your medicine. I was very disappointed since I have been battling high cholesterol for many years. I thought I had found the answer to my problem in your product. I'm sure your product has worked for many other people, but it definitely did not work for me.


Reviewed on
3.0 out of 5 stars

trying to lower my total chol, have used the Advanced Chol Sol for 3 mos and LDL went up, HDL went up, TRIG went up, ratio went down. don't know what all that means, but i'm going to continue to use this product in conjunction w/red yeast rice and complex vit b for the liver.


Reviewed on
3.0 out of 5 stars

I have high cholesterol and Dr. Sinatra's ACS is affecting the numbers, but it is slow. I'd like to see a quicker effect, but I'm staying the course because i do see results. And, it gives me an alternative to the many prescribed medications, especially statins, which have not been helpful.


Reviewed on
5.0 out of 5 stars

I love it. There are NO side effects and I feel wonderful. My doctor thinks it's all in my mind, but the numbers proved it.


Reviewed on
3.0 out of 5 stars

I have a very healthy diet and limit my intake of saturated fat. I exercise three or more times each week, but I am still plagued by high cholesterol. I am at a good weight for my height and do not smoke. I turned to supplements when my doctor recommended a statin drug. I have been taking Advanced Cholesterol Solutions for three months. I take two capsules daily. My total cholesterol has gone down slightly, and my HDL has improved slightly. Unfortunately, my triglycerides remain (high). I was hoping for more of an improvement, but I will take what I can get to avoid using a (prescription) drug! I intend to continue with the Advanced Cholesterol Solutions for another three months with the hope of continued improvement. I am also taking Omega Plus Resveratrol and Dr. Sinatra's probiotic. I have been on both of those supplements for over six months.


Reviewed on
5.0 out of 5 stars

Have been taking the omega plus for about a year. thought I would try the cholesterol because Dr. wanted me on statins and I want nothing to do with them. after only 2 months taking one pill a day, my numbers dropped like a rock. I am so pleased. did nothing else. I ate the same, as I am not a junk eater anyways. did not lose one ounce off my weight. very, very happy.


Reviewed on
5.0 out of 5 stars

Although my doctor is still unhappy with my total cholesterol numbers, I am excited: my LDL is the lowest it has been in years. I argue with my doctors over my total numbers because I have always had high HDL. My total numbers were still very high this time, too, because my HDL was also higher than it has ever been. I have continued taking this supplement and am anxious to see what my tests are after a year.

See why Dr. Sinatra partners with Healthy Directions

Product Quality

  • Manufactured to exacting standards using highest quality raw materials
  • Produced under our own SOPs that meet or exceed FDA GMPs
  • Every batch tested to verify purity and potency specifications are met
  • Specific product testing is listed in the Certificate of Quality
  • Quality assured with our Triple Testing Philosophy™
  • Backed by our 100% satisfaction guarantee

How do I know I am choosing the best supplements?