Grapefruit Juice and Medication Interaction

Filed Under: General Health
Last Reviewed 06/23/2015

Grapefruit Juice and Medication Interaction

Grapefruit and its juice can create medication interactions with many types of drugs, from antibiotics to antipsychotics. These drugs should never be combined with grapefruit. Also, as a general rule, always remember to ask about any possible medication interactions with other drugs or foods whenever your doctor prescribes you a new medication.

Avoid Medication Interaction With Grapefruit

Aldosterone inhibitors:
eplerenone (Inspra)

amiodarone (Cordarone) 
quinidine (Quinaglute, Quinidex, Quinora)

carvedilol (Coreg) 
losartan (Cozaar)

Blood thinners:
warfarin (Coumadin)

Calcium channel blockers
felodipine (Plendil) 
nicardipine (Cardene) 
nifedipine (Adalat, Procardia) 
nimodipine (Nimotop) 
isradipine (DynaCirc) 
verapamil (Isoptin, Verelan, Calan, Bosoptin, Covera-HS)

Statin drugs
atorvastatin (Lipitor) 
lovastatin (Mevacor) 
simvastatin (Zocor, Vytorin)

carbamazepine (Tegretol

sertraline (Zoloft) 
trazodone (Desyrel) 
nefazodone (Serzone)
clomipramine (Anafranil)

fexofenadine (Allegra)

Anti-anxiety drugs
diazepam (Valium) 
midazolam (Versed) 
triazolam (Halcion) 
buspirone (BuSpar)

methylprednisolone, oral (Medrol) 
budesonide (Pulmicort, Rhinocort)

cyclosporine (Sandimmune, Neoral) 
tacrolimus (Prograf)

Protease inhibitors
ritonavir (Norvir) 
nelfinavir (Viracept) 
saquinavir (Invirase, Fortovase)

DISCLAIMER: The content of is offered on an informational basis only, and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified health provider before making any adjustment to a medication or treatment you are currently using, and/or starting any new medication or treatment. All recommendations are "generally informational" and not specifically applicable to any individual's medical problems, concerns and/or needs.

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