Grapefruit Juice and Drug Interactions

Grapefruit and its juice can create drug interactions with many types of medications, from antibiotics to antipsychotics. These drugs should never be combined with grapefruit. Also, as a general rule, always remember to ask about any possible interactions with other drugs or foods whenever your doctor prescribes you a new medication.

Aldosterone inhibitors:
eplerenone (Inspra)

Anti-arrhythmics:
amiodarone (Cordarone)
quinidine (Quinaglute, Quinidex, Quinora)

Antihypertensives:
carvedilol (Coreg)
losartan (Cozaar)

Blood thinners:
warfarin (Coumadin)

Calcium channel blockers:
felodipine (Plendil)
nicardipine (Cardene)
nifedipine (Adalat, Procardia)
nimodipine (Nimotop)
isradipine (DynaCirc)
verapamil (Isoptin, Verelan, Calan, Bosoptin, Covera-HS)

Statin drugs:
atorvastatin (Lipitor)
lovastatin (Mevacor)
simvastatin (Zocor, Vytorin)

Anticonvulsants:
carbamazepine (Tegretol

Antidepressants:
sertraline (Zoloft)
trazodone (Desyrel)
nefazodone (Serzone)
clomipramine (Anafranil)

Antihistamines:
fexofenadine (Allegra)

Anti-anxiety drugs:
diazepam (Valium)
midazolam (Versed)
triazolam (Halcion)
buspirone (BuSpar)

Corticosteroids:
methylprednisolone, oral (Medrol)
budesonide (Pulmicort, Rhinocort)

Immunosuppressants:
cyclosporine (Sandimmune, Neoral)
tacrolimus (Prograf)

Protease inhibitors:
ritonavir (Norvir)
nelfinavir (Viracept)
saquinavir (Invirase, Fortovase)