Doctor-recommended support for healthy cholesterol ratios, blood pressure & overall heart health

Omega Q Plus (60 softgels, 30-day supply) | heart health supplements

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1 Bottle
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Was: $131.96
Now: $98.97
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Was: $230.93
Now: $164.95

No other natural solution can deliver what Omega Q Plus® can:

  • A tremendous boost of daily energy
  • Healthy blood pressure levels
  • Optimal HDL and triglyceride levels
  • Improved circulation
  • Natural anti-inflammatory power
  • Superior vision support
  • Sharp, focused brain power
  • And so much more…

Customers say:

“Since I started taking Omega Q Plus, my energy level has increased and I feel great. I will always take this supplement!”*
— Deanie

My cholesterol is better than it ever has been in my life (I’m 66). Triglycerides have improved greatly too!”*
— Margaret H.

“I love this supplement. Not only do I feel more energetic, but I am thrilled to be protecting my heart…this is the best insurance that money can buy.”*
— Keswick

*Results may vary.

Here’s how: DHA-rich Calamarine® Omega-3 Oil—the discovery that makes ordinary fish oil obsolete

Calamarine omega-3 oil has far MORE heart-healthy DHA than ordinary fish oil! And growing research suggests that DHA works the hardest to improve your blood pressure, blood vessel health, and circulation, plus support your brain, nerves, eyes, and colon.

Calamarine oil isn’t sourced from fish. It’s a pure and potent extract of deep-water calamari (squid). This is good news on many fronts. For one, they are an extremely eco-friendly, sustainable source of omega-3 fatty acids.

Plus, Calamarine has NO fishy aftertaste and won’t cause “fishy burps.” But that’s only one part of the story…

Bioavailability of CoQ10
Benefits and features of Omega Q Plus CoQ10 and Calamarine omega-3 DHA supplement versus ordinary fish oil0

Highly absorbable Hydro Q-Sorb® CoQ10—for incredible energy and antioxidant protection

Cardiologists often call CoQ10 the “miracle nutrient” because it fuels your cellular power plants. This is especially important for your heart—a muscle that requires huge amounts of oxygen and energy to function. Plus, CoQ10 acts as a potent antioxidant—hunting and destroying free radicals that can damage your heart health and overall well-being.

Omega Q Plus features a patented, cutting-edge form of CoQ10 called Hydro Q-Sorb, which is 8 times better absorbed than ordinary powdered CoQ10 for:

  • A strong, healthy heart
  • Normal blood pressure
  • Enhanced circulation
  • Outstanding overall cardiovascular function
  • Abundant cellular, physical, and mental energy
  • Superior antioxidant protection
  • Healthy aging

But that’s not all…
Four powerful nutrients round out my #1 recommended heart supplement

In addition to the cardio-power pair of Hydro Q-Sorb CoQ10 and Calamarine omega-3 oil, Omega Q Plus also gives you 4 additional heart-healthy nutrients for unparalleled nutritional support:

  1. L-Carnitine—works hand in hand with Hydro Q-Sorb to increase energy and improve cardiovascular health
  2. Folic Acid—an important player in the fight against unhealthy homocysteine levels and an essential nutrient for keeping your blood vessels healthy
  3. Vitamin B6—vital to over 60 different enzyme processes in your body and considered one of the key vitamins for overall health
  4. Vitamin B12—works in combination with other B vitamins to lower homocysteine levels, enhance energy production, protect cardiovascular health, and even boost your intestinal well-being and immunity!

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Ingredients and Dosage

Doctor’s Suggested Use: Take 2 softgels once daily with a meal. For added support, take 2 softgels twice daily with a meal.

Serving Size: 2 Softgels
Servings Per Container
: 30

Ingredient Amount Per Serving % DV
Calories 10  
Calories from Fat 10  
Total Fat 1 g 2%*
Cholesterol <5 mg 1%
Vitamin B6 (as pyridoxine HCI, pyridoxal-5-phosphate) 30 mg 1,500%
Folic Acid 400 mcg 100%
Vitamin B12 (as cyanocobalamin) 750 mcg 12,500%
Calamarine®♦ Oil Concentrate (from squid) 1,250 mg
DHA (docosahexaenoic acid) (as ethyl esters) 350 mg
EPA (eicosapentaenoic acid) (as ethyl esters) 150 mg
L-Carnitine (as fumarate) 200 mg
Coenzyme Q10 (as ubiquinone) 50 mg
* Percent Daily Values are based on a 2,000 calorie diet.
‡ Daily Value (DV) not established

Other ingredients: Gelatin, gamma cyclodextrin, glycerin, medium chain triglycerides, sunflower lecithin, beeswax, natural lemon flavor, annatto seed extract, sunflower oil

Note: Pregnant or lactating women should consult a health care professional before taking this product.
Keep out of reach of children.

Calamarine® is a registered trademark of Pharma Marine AS.

§ Hydro Q-Sorb®, CoQ10Pure®, and Omega Q Plus® are registered trademarks of Tishcon Corp.


Displaying 1-10 of 85


Reviewed on
5.0 out of 5 stars

After taking omega q plus for 5 weeks blood pressure readings are excellent. This started after the first 5 days. Will continue to take this supplement.


Reviewed on
3.0 out of 5 stars

After 90 days lowered LDL [and], raised HDL [slightly].


Reviewed on
5.0 out of 5 stars

I can walk fast now and I'm always on the go.


Reviewed on
5.0 out of 5 stars

Great product we've been using for several years and has definitely helped our numbers say in the healthy range. Would like to see more CoQ 10 than the 50 mg. now in the daily dosage.


Reviewed on
4.0 out of 5 stars

I have not been able to do any blood work yet to see what OQP has helped. Blood pressure is a ok and I will be taking More test to see how it is working. I will give you more feedback a little later. Thanks, Charlie


Reviewed on
5.0 out of 5 stars

Since I have been taking Omega Q Plus with the Vitamin D my blood pressure has gone down to safe level. My doctor was mighty impressed.


Reviewed on
5.0 out of 5 stars

I had extremely high blood pressure and was on 4 pres meds which helped very little. I started taking Omega Q plus about 2 years ago and BP has been in normal range ever since. I love it.


Reviewed on
5.0 out of 5 stars

Let's put it this way! There is no fishy after taste, whatsoever! No fishy burps... EVER! I haven't fallen sick or felt any aches and pains (10 months)! My blood pressure was [good] at last reading. I will know more about my cholesterol ratios in February! Thank you for standing behind your formula and making yourself available to "friends" on Facebook, by personally responding to questions of personal concern. It speaks volumes about you, Dr. Sinatra! -Stuart-


Reviewed on
5.0 out of 5 stars

i have a few medical conditions, [ ] muscle aches and pains. since putting this in my daily routine i have been feeling better. i just added the weight loss vitamin and ordered the aches, pain, back and muscle supplement. i hope this combination will really put me in better shape and try to stop some of my medications.


Reviewed on
4.0 out of 5 stars

I have been on this for 30 days and it seems to be working this is a very good supplement

Science and Quality

See why Dr. Sinatra partners with Healthy Directions

A high-quality source of heart-healthy DHA

The ability of the body to convert plant-based omega-3s (ALA) to EPA, and subsequently DHA, is very low, even in healthy individuals. And DHA is especially difficult to obtain from plant-based omega-3s. Virtually no DHA is converted from ALA: One study showed that only 0.04% is converted to DHA1 and another study showed healthy males converted only 4%.2

You would need to eat about 4 teaspoons of flaxseed oil to get the same amount of DHA in Omega Q Plusor about 1 cup of walnuts…or about 7 tablespoons of canola oil.

Why is DHA important to heart health?

Blood pressure

Research shows that DHA supplementation has a better effect in promoting normal blood pressure levels than EPA. In a double-blind, placebo-controlled study, subjects were given purified supplements of EPA or DHA (4 grams) or a placebo for 6 weeks. Researchers found that DHA was superior to EPA for supporting healthy blood pressure levels. DHA (but not EPA) also helped reduce heart rate. It was also found that EPA supplements had no effect on raising blood phospholipid levels of DHA, indicating that the body has a difficult time converting EPA supplements to DHA.3

DHA is also better at improving vasodilation and endothelial function (as measured by forearm blood flow) in these same subjects.4

Blood Lipids

EPA and DHA have been shown to have favorable effects on blood lipids, including triglycerides, HDL cholesterol, and lipid particle size, all important measures of cardiovascular health. While it appears that both EPA and DHA help to lower triglycerides (dosages greater than 2 grams daily), research suggests that DHA is the omega-3 that is responsible for increasing HDL cholesterol levels in the body.

Overall heart health

In a study of postmenopausal women, those with the highest levels of DHA (and not EPA or ALA) showed significantly better coronary artery health over a 3-year period.5 Similarly, in men, research shows that higher levels of DHA (and lower levels of saturated fat) is associated with better coronary artery health.6

1 Burdge GC, et al. Br J Nutr 2003;90(2):311–21.
2 Emken EA, et al. Biochim Biophys Acta 1994;1213(3):277–88.
3 Mori TA, et al. Hypertension 1999;34(2):253–60.
4 Mori TA, et al. Circulation 2000;102(11):1264–69.
5 Erkkila A, et al. J Lipid Res 2006;47(12):2814–19.
6 Simon JA, et al. Am J Epidem 1995;142(5):469–76.

Consumer Lab Approval - Coenzyme Q 10

Omega Q Plus has been certified as “Approved Quality” by To read the results of the test, click here.

Product Quality

How do I know I am choosing the best supplements?

How is this form of CoQ10 more bioavailable?

Coenzyme Q10 is one of the more difficult compounds to absorb because it is a large fat soluble molecule. Hydro Q-Sorb®, an all-natural, free flowing powder combines CoQ10 with gamma-cyclodextrin, a type of glucose molecule with a hydrophobic (fat loving) center and a hydrophilic (water loving) exterior. It essentially binds to and wraps around the CoQ10 molecule, allowing the CoQ10 to become water dispersible, making it easier to absorb.

Does the CoQ10 (Hydro Q-Sorb) change to ubiquinol from ubiquinone?

CoQ10 exists mainly in its reduced form—ubiquinol—and in this form it is used to scavenge and neutralize free radicals in the mitochondria. CoQ10 also fuels your mitochondrial energy production and the body converts ubiquinol into its oxidized state—ubiquinone—for this process. The body is constantly either reducing ubiquinone to ubiquinol when it needs more antioxidant power, or it is converting ubiquinol into ubiquinone when your body needs to rev up mitochondrial energy production. When you supplement with CoQ10, your body is going to determine how it needs the CoQ10 to be used.

I'm reading more and more about the methylcobalamin form of vitamin B12 and wonder why Dr. Sinatra does not use this form in his supplements?

Cyanocobalamin is the form of B12 that is used in the research that Dr. Sinatra uses for his B12 claims in OQP.

Dr. Sinatra's opinion is that cyanocobalamin is an effective, inexpensive foundation, but he acknowledges that other forms of B12 may be more beneficial for targeted needs. Methylcobalamin and 5-deoxyadenosyl cobalamin are the forms of vitamin B12 used in the human body, and cyanocobalamin is readily converted to 5-deoxyadenosyl and methylcobalamin in the body. There have been no reported adverse effects of cyanide poisoning or toxicity when using our doses of cyanocobalamin.

What are the ingredient standardizations?


Is the formula kosher?


Is the formula and capsule vegetarian?

No, the softgel is made of gelatin, which comes from bovine (cow) and porcine (pig) sources.

Is the formula sodium free?

Yes. There are also no preservatives, artificial colors, or artificial flavors.

What are the “other ingredients” used in this product?

Gelatin, glycerin, medium chain triglyceride oil, gamma cyclodextrin, beeswax, soy lecithin, annatto seed extract, and natural lemon flavor.

Which of the ingredients are natural and which are synthetic?

All of the ingredients are naturally sourced.

Can I take this product with Dr. Sinatra’s other recommended nutritional supplements?

Yes. Omega Q Plus should be taken with a high-quality multinutrient such as the Heart Healthy Multivitamin.

How should I store the product?

To preserve the quality and freshness, keep the bottle tightly closed and store it in a cool, dry place (59°-86°F). Do not refrigerate.

Is this product tested for lead, mercury, and other heavy metals?

Every batch of Healthy Directions products is tested for lead and heavy metals. Each is delivered to Healthy Directions with a Certificate of Analysis from the manufacturer stating that the products are free of heavy metals or within the limits set by California’s Proposition 65—the most stringent in the country.

Does this product undergo independent laboratory testing?

Each month, Healthy Directions randomly selects several of its products and sends them to independent laboratories to make sure that they meet safe levels for heavy metals and pesticides, as well as label claim. In addition, Healthy Directions requires each of its manufacturers to fully test each of our products in independent labs twice a year.