Relief for everyday aches and pains that's good for your heart and gentle on your stomach

Omega-3 Joint Relief with Turmeric (60 softgels, 30-day supply) | Joint Relief Supplements

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1 Bottle
$39.99
Buy 3, Get 1 FREE
Was: $159.96
Now: $119.97
Buy 5, Get 2 FREE
Was: $279.93
Now: $199.95

Omega-3 Joint Relief with Turmeric:

  • Features Turmacin, clinically shown to relieve joint discomfort by 42%1
  • Includes UC-II, collagen extract, clinically shown to provide MORE pain relief than glucosamine and chondroitin
  • Helps to reduce exercise-induced joint discomfort as well as joint creaking and popping
  • Alleviates joint stiffness and improves physical function
  • Supports blood vessel health and endothelial function
  • Reduces oxidative stress and promotes normal inflammatory response
  • Supports cardiovascular health
  • Developed by integrative cardiologist Dr. Stephen Sinatra


Science has recently uncovered two powerful new ingredients—Turmacin™ turmeric extract and UC-II® collagen extract—that offer tremendous relief from everyday aches and pains, that's also good for your heart and gentle enough to be used everyday.

These two clinically-studied nutrients are the foundation of my joint health formula…Omega-3 Joint Relief with Turmeric.

Advanced turmeric extract

For centuries, turmeric (Curcuma longa) has been revered for its pain relieving properties. But, the curcumin turmeric extract used in most joint relief supplements is hard to digest, which limits its ability to be absorbed and used by the body.

Thanks to its unique molecular structure Turmacin contains no hard-to-digest curcuminoids so it can be better utilized by your body. Plus Turmacin has also been clinically studied for its effectiveness.

In a randomized, placebo-controlled trial that studied the effects of 1,000 mg of Turmacin daily (the same dose you get in Omega-3 Joint Relief with Turmeric), participants used three different, well-recognized tests to measure pain reduction. The results were consistent and astounding.1

Turmacin is able to deliver these tremendous benefits because it works across multiple pathways to promote a healthy inflammatory response, which is essential for healthy joints.

86% of participants were pain free after 42 days!

Patented undenatured type II collagen

A second nutrient breakthrough in Omega-3 Joint Relief with Turmeric is UC-II. This patented undenatured type II collagen helps block collagen breakdown and is clinically shown to be more effective than glucosamine and chondroitin for reducing pain.

UC-II® collagen is extracted using a low-heat, non-enzymatic process that preserves its natural form. This allows it to short-circuit the enzymes that contribute to cartridge breakdown, protecting against the inflammation associated with normal wear and tear of the joints.

PLUS, Omega-3 Calamarine for added joint-health support

For added joint health support, and for its heart healthy benefits, I added a 500 mg daily dose of omega-3 Calamarine® to my Omega-3 Joint Relief with Turmeric formula. Unlike ordinary fish oils, this pure, potent source of omega-3’s is naturally rich in DHA, for added joint, heart, brain and eye support.

I believe that Omega-3 Joint Relief offers a unique combination of joint and heart health benefits that's both gentle and effective for everyday use.

What Our Customers Say:

"Thank you! …I just walked down the steps like I did 20 years ago."*

— Online review

"It has helped with all my joints…"*

— Online review

"…I consider it a miracle pill!"*

— Online review

*Results may vary.

 

Dr. Sinatra Says:

Dr. Stephen Sinatra
 

"When your joints hurt, it impacts all aspects of life from how you move to how you feel, making even the simplest tasks challenging. With Omega 3 Joint Relief I wanted to offer a formula that was both effective for everyday aches and pains and also good for your heart."

 
 

1 Maddhu K, et al. Inflammopharmacol; DOI 10.1007/s10787-012-0163-3.

Calamarine Oil

What Our Customers Say:

"Thank you! …I just walked down the steps like I did 20 years ago."*

— Online review

"It has helped with all my joints…"*

— Online review

"…I consider it a miracle pill!"*

— Online review

*Results may vary.

 

Dr. Sinatra Says:

Dr. Stephen Sinatra
 

"When your joints hurt, it impacts all aspects of life from how you move to how you feel, making even the simplest tasks challenging. With Omega 3 Joint Relief I wanted to offer a formula that was both effective for everyday aches and pains and also good for your heart."

 
 
86% of participants were pain free!

Ingredients and Dosage

Doctor's Suggested Use: Take 2 softgels once daily with a meal. For added support, take 2 softgels twice daily with a meal.

Serving Size: 2 Softgels
Servings Per Container: 30

Ingredient Amount Per Serving % DV
Calories 10  
Calories from Fat 10  
Total Fat 1 g 2%
Cholesterol <5 mg 1%
Turmacin®♦ Turmeric Extract (rhizome) 1 g *
Calamarine®§ Oil Concentrate (from squid) 500 mg *
DHA (docosahexaenoic acid) 140 mg *
EPA (eicosapentaenoic acid) 60 mg *
UC-II®◊ Standardized Chicken Cartilage (Providing 10 mg Undenatured Type II Collagen) 40 mg *
Percent Daily Values are based on a 2,000 calorie diet.
* Daily Value (DV) not established

Other ingredients: Gelatin, sunflower oil, glycerin, sunflower lecithin, caramel color, yellow beeswax, silicon dioxide

Note: Pregnant or lactating women should consult a health care professional before taking this product.
Keep out of reach of children.

As ethyl ester.
Turmacin® is a registered trademark of Natural Remedies Pvt Ltd.

Calamarine® is a registered trademark of Pharma Marine AS.

is a registered trademark of InterHealth N.I.

brand undenatured type II collagen (U.S. Patents 7,846,487, 7,083,820 and EPO Patent EP1435906B1; Canadian patent CA 2459981C; and Japanese Patent JP4800574B2).

Science and Quality

The science behind Turmacin™ (Curcuma longea)

Turmacin helps provide relief for painful joints, improved joint mobility and function, and a proper inflammatory response as assessed by three different, well-regarded pain assessment scales: VAS, WOMAC, and CGIC.

A randomized, single-blind, placebo-controlled trial assessed the effects of 1000 mg/day Turmacin vs. placebo in 120 patients (average age 57) with knee pain for more than 42 days.

Visual Analog Scale (VAS):

  • Measures subjective characteristics (pain) in the form of a response scale scored between 0 and 100 (0 = no pain to 100 = most severe pain)
  • Turmacin had a significantly greater improvement/reduction to baseline and placebo
    • 42% reduction from baseline in 21 days
    • 71% reduction from baseline in 42 days

Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

  • A functional assessment pertaining to an affected knee joint / joints with 24 questions
  • Pain graded on 1-5, stiffness 6-7, and physical functional difficulty 8-24. The patients' response is graded qualitatively (0 = none, 1 = mild, 2 = moderate, 3 = severe, 4 = extreme) with a maximum score of 96
  • Turmacin had a significantly greater improvement / reduction to baseline and placebo
    • 33% reduction from baseline in 21 days
    • 51% reduction from baseline in 42 days

Clinician Global Impression Change (CGIC)

  • Employed to assess improvement in patients' overall condition
  • Rated based on the clinical examination on day 21 and 42. The scale range was from 0 to 7 ['0' = no pain and '7' = worst pain].
  • Patients are evaluated by an orthopedic consultant and assessed on the presence or absence of joint tenderness, crepitus (crackling and popping in the joints), limitation of movement, and subluxation of joint
  • Turmacin had a significantly greater improvement / reduction to baseline and placebo
    • 27% reduction from baseline in 21 days
    • 57% reduction from baseline in 42 days

Joint tenderness: There was a significant reduction in the number of patients with the presence of joint tenderness from an initial number of 29 patients to 4 patients at the end of the 42-day study.

Joint crepitus: There was a significant reduction in the number of patients with joint crepitus for the Turmacin group.

Mobility of joints: There was a significant reduction in the number of patients with a limitation in the movement of their joints for the Turmacin group.1

The science behind UC-II®

UC-II outperforms glucosamine and chondroitin (G+C) in supporting pain relief, joint discomfort, and immobility as measured by WOMAC, VAS, and Lequesne's Functional Index (LFI).

In a randomized, double-blind clinical study, 52 patients (average age 58) were assigned to take either 40 mg of UC-II or 1,500 mg glucosamine + 1,200 mg chondroitin (G+C) over 90 days to assess safety and efficacy.2

Visual analog scale (VAS):

  • UC-II reduced VAS by 40% compared to 15% for (G+C)

Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC):

  • Treatment with UC-II reduced WOMAC scores by 33% compared to 14% for (G+C) after 90 days

Lequesne's Functional Index (LFI):

  • Used to determine the effect of the different treatment groups on pain during daily activities
  • UC-II reduced the LFI score by 20% compared to 6% for (G+C)

UC-II can help support and alleviate joint discomfort during and after exercise as well as improve flexibility and mobility in physically active healthy subjects.3

In a randomized, double-blind, placebo-controlled, adaptive-designed pilot study, 55 healthy subjects (ages 30–65) experiencing joint discomfort upon strenuous exercise took either 40 mg/day of UC-II or placebo before bed over 120 days while continuing their normal diet and exercise regimens. Subjects were tested at 30-day intervals from baseline to 120 days by inducing physical stress through a standardized stepmill procedure.

  • Significant improvement in knee extension at 90 days (compared to baseline) and 120 days (compared to baseline and placebo)
  • The minimum time to onset of joint discomfort (while exercising) was significantly better than baseline at day 90 and day 120. No significant changes in placebo.
  • Longer exercise duration before discomfort occurred
  • Maximum time to offset joint discomfort (after exercising) was significantly faster at days 60, 90, and 120 compared to baseline
  • Faster recovery from joint discomfort

The science behind Calamarine®

  • Increased consumption of omega-3 fatty acids, especially those from fish and fish oil, is associated with overall cardiovascular health.4
  • In a double-blind, placebo-controlled study, subjects were given purified supplements of EPA or DHA (4 grams) or placebo for 6 weeks. Researchers found that DHA was superior to EPA in promoting healthy blood pressure levels.5 Both EPA and DHA have been shown to play a role in blood platelet aggregation, which in part regulates blood viscosity.6,7
  • In a study of postmenopausal women, those with the highest levels of DHA (and not EPA or ALA) showed significantly better coronary artery health over a 3-year period.8 Similarly, in men, research shows that higher levels of DHA (and lower levels of saturated fat) are associated with better coronary artery health.9
  • Omega-3 supplementation helps to reduce oxidative stress markers in the body, which may explain its beneficial effect on the cardiovascular system.10,11
  • In a recent study of 124 healthy men and women, examining blood levels of omega-3 fatty acids and C-reactive protein (CRP), a marker for cardiovascular health, researchers found that those with the highest levels of EPA and DHA had the lowest levels of CRP.12
  • Taking fish oil helps replace some of the arachidonic acid (an omega-6) in cell membranes with the more desirable omega-3 fatty acids.13 This leads to a better ratio of essential fatty acids which helps promote a normal inflammatory response by balancing prostaglandins and leukotrienes—hormone-like substances—that impact a person's cardiovascular health.
  • Fish oil supplementation has a beneficial effect on endothelial function and vascular tone in healthy subjects.14
  • Omega-3s support arterial health by supporting proper blood vessel dilation, arterial flexibility, and vascular functions.15

1Madhu K et al. Inflammopharmacol; DOI 10.1007/s10787-012-0163-3
2Crowley D., et al. Int. J. Med. Sci. 2009;6(6),312-1.
3Udani J, et al. A randomized, double-blind, placebo-controlled study in healthy volunteers. 2013; Unpublished.
4Yam D, et al. Harefuah. 2001;140(12):1156-8,1230.
5Mori T, et al. Hypertension. 1999;34(2):253-60.
6Woodman R, et al. Atherosclerosis. 2003;166(1):85-93.
7Park Y, et al. Lipids. 2002;37(10):941-6.
8Erkkila A, et al. J Lipid Res. 2006;47:2814-9.
9Simon A, et al. Am J Epidem. 1995;142(5):469-76.
10Jain S, et al. J Assoc Physicians India. 2002;50:1028-33.
11Mori T, et al. Free Radic Biol Med. 2003;35(7):772-81.
12Micallef M, et al. Eur J Clin Nutr. 2009;63:1154-6.
13Calder P. Proc Nutr Soc. 2002;61(3):345-58.
14Khan F, et al. Cardiovasc Res. 2003;59(4):955-62.
15Nestel P, et al. Am J Clin Nutr. 2002;76:326-30.

See why Dr. Sinatra partners with Healthy Directions

Product Quality

The Science Behind UC-II

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