Does Aspirin Therapy Really Work?

Filed Under: Heart Health
Last Reviewed 02/06/2014

Pop an aspirin. Prevent clots. Save your life. 

If you have cardiovascular problems, you’ve probably heard that aspirin is a popular and inexpensive approach to help keep blood thin and prevent blood clots that can lead to heart attacks and strokes.

Aspirin’s appeal is its ability to block the formation of thromboxane A2. Thromboxane constricts blood vessels and allows platelets to clump together and form clots at the site of wounds. The thinking behind aspirin therapy is that if you reduce the amount of thromboxane produced, you help prevent blood clots from forming and, subsequently, reduce a cardiac event, and reduce heart risk factors.

Though doctors and holistic health practitioners often prescribe aspirin for both primary and secondary prevention, we are always concerned about the threat of gastrointestinal bleeding. That’s why you want to be sure that you’re benefitting from the aspirin before you continue to take it every day.

This challenge may now be overcome with a new test called AspirinWorks.  Now, a simple urine sample can show your doctor whether aspirin therapy is effective for you. This test measures the level of 11-dehydrothromboxane B2, an end product of thromboxane metabolism. At you can learn more about the test.

If your test results show a low level of thromboxane metabolites in your system, it means your prescribed aspirin therapy is working. If your results are higher up the scale, you would likely benefit from increasing your dosage. However, if you’re already taking the maximum dosage of aspirin, you’re probably aspirin-resistant.

In that case, it’s best to stop the daily aspirin and not risk the gastrointestinal side effects. Though that may sound frightening, you need to keep in perspective that if you’re aspirin-resistant, that daily pill wasn’t doing you any good anyway.

For more information on preventing blood clots and other cardiovascular problems, visit

DISCLAIMER: The content of is offered on an informational basis only, and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified health provider before making any adjustment to a medication or treatment you are currently using, and/or starting any new medication or treatment. All recommendations are "generally informational" and not specifically applicable to any individual's medical problems, concerns and/or needs.

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