Daily Health Center

Grapefruit Juice and Drug Interactions—The Complete List

Grapefruit and its juice can create drug interactions with many types of medications, from antibiotics to antipsychotics. These drugs should never be combined with grapefruit. Also, as a general rule, always remember to ask about any possible interactions with other drugs or foods whenever your doctor prescribes you a new medication.

Aldosterone inhibitors:
eplerenone (Inspra)

Anti-arrhythmics:
amiodarone (Cordarone)
quinidine (Quinaglute, Quinidex, Quinora)

Antihypertensives:
carvedilol (Coreg)
losartan (Cozaar)

Blood thinners:
coumarin 
warfarin (Coumadin)

Calcium channel blockers:
felodipine (Plendil)
nicardipine (Cardene)
nifedipine (Adalat, Procardia)
nimodipine (Nimotop)
isradipine (DynaCirc)
verapamil (Isoptin, Verelan,  Calan, Bosoptin, Covera-HS)

Statin drugs:
atorvastatin (Lipitor)
lovastatin (Mevacor)
simvastatin (Zocor, Vytorin)

Anticonvulsants:
carbamazepine (Tegretol)
Antidepressants:
sertraline (Zoloft)
trazodone (Desyrel)
nefazodone (Serzone)

clomipramine (Anafranil)

Antihistamines:
fexofenadine (Allegra)

Anti-anxiety drugs:
diazepam (Valium)
midazolam (Versed)
triazolam (Halcion)
buspirone (BuSpar)

Corticosteroids:
methylprednisolone, oral (Medrol)
budesonide (Pulmicort, Rhinocort)

Immunosuppressants:
cyclosporine (Sandimmune, Neoral)
tacrolimus (Prograf)

Protease inhibitors:
ritonavir (Norvir)
nelfinavir (Viracept)
saquinavir (Invirase, Fortovase)

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